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Medical Assistant vs. Physician Assistant: What’s the Difference?

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By: All Allied Health Staff

Updated: June 11, 2026

Home » Blog » Medical Assistant vs. Physician Assistant

Key Takeaways

  • Medical assistants are entry-level roles handling administrative and clinical tasks, while physician assistants perform advanced duties alongside physicians.
  • The education requirements and job duties for medical assistants and physician assistants differ significantly, leading to different salary expectations.
  • Medical assistants often pursue specialized roles, while physician assistants can specialize further through additional education and training.

Just because a health care career has the word “assistant” in its job title, it doesn’t necessarily mean your education will be less strenuous or a less of a commitment to time and effort than other roles—or that your duties will be confined to that of an aide and helper. A good example of two health care careers that could not be more different—but might be confusing due to assistant being in the title—are Medical Assistant and Physician Assistant.

Short and sweet, a medical assistant is more of an entry- to-mid level career while as a physician assistant you will assist and perform advanced duties with a practicing physician.

So, while these two in-demand health care professions sound an awful lot alike, they actually share very little in common when it comes to day-to-day tasks, education requirements, and salary. There are vastly different time and commitment levels needed for you to earn your degree, and the job duties and expertise required are also at opposite ends of the spectrum.

Medical assistants handle a wide variety of entry-level administrative and clinical tasks, whereas physician assistants are licensed health care providers who diagnose and treat patients under the supervision of a physician.

If you’re just entering the health care field, you’ll want to consider a medical assistant career. If you’ve been in the field, have your bachelor’s degree, and are looking to move up the ladder, earning your master’s degree and pursuing your national certification from an accredited PA training program may be the course for you.

Main Differences Between Medical and Physician Assistants

Here are all of the key differences for both careers side-by-side:

Job Duties


Medical Assistant

Physician Assistant

  • Perform administrative tasks, such as updating medical records and arranging for lab services, and clinical duties, such as taking medical histories and recording vital signs.
  • Practice medicine under a physician’s supervision, often serving as the principal health care provider in rural or inner-city clinics.

Education


Medical Assistant

Physician Assistant

Licensing and Certification


Medical Assistant

Physician Assistant

  • To become a certified medical assistant, you must graduate from an accredited medical assistant training program and pass a certifying exam. You can work as an MA without being certified, but most employers and some states require certification for MAs to do things like draw blood.
  • You must be licensed by a state board to practice as a physician assistant. To be eligible for a PA license, you have to pass a national certifying exam, which requires that you graduate from an accredited physician assistant training program.

Median Annual Salaries

The difference in salary between medical assistants and physician assistant roles is notable. Take a look at median annual salaries, as reported by the U.S. Bureau of Labor Statistics.

Medical Assistants

National data

Median Salary: $45,690

Projected job growth: 12.9%

10th Percentile: $36,050

25th Percentile: $38,470

75th Percentile: $49,180

90th Percentile: $59,310

Projected job growth: 12.9%

State data

State Median Salary Bottom 10% Top 10%
Alabama $36,100 $29,630 $45,040
Alaska $52,560 $46,060 $65,040
Arizona $45,940 $38,100 $51,310
Arkansas $37,760 $30,840 $46,060
California $49,660 $39,290 $77,300
Colorado $48,400 $39,130 $59,760
Connecticut $47,430 $38,480 $59,530
Delaware $44,490 $36,540 $57,280
District of Columbia $51,050 $39,620 $76,900
Florida $43,680 $35,880 $49,040
Georgia $41,600 $34,270 $51,430
Hawaii $48,410 $38,580 $60,030
Idaho $44,700 $35,500 $56,740
Illinois $46,090 $36,400 $56,590
Indiana $45,110 $37,060 $50,480
Iowa $45,480 $36,730 $54,960
Kansas $39,510 $35,140 $48,300
Kentucky $39,270 $32,950 $47,940
Louisiana $36,320 $28,970 $44,460
Maine $47,580 $40,220 $59,220
Maryland $46,410 $36,930 $57,250
Massachusetts $49,460 $43,280 $61,870
Michigan $39,870 $35,000 $48,330
Minnesota $50,480 $40,110 $60,100
Mississippi $35,360 $29,210 $45,070
Missouri $40,440 $35,810 $48,360
Montana $46,820 $38,670 $56,770
Nebraska $47,370 $37,940 $59,450
Nevada $45,200 $37,400 $55,120
New Hampshire $48,020 $39,640 $60,100
New Jersey $47,210 $37,010 $58,070
New Mexico $39,230 $34,600 $47,850
New York $48,000 $37,280 $59,480
North Carolina $45,140 $36,010 $50,850
North Dakota $45,980 $37,650 $58,230
Ohio $42,810 $36,050 $48,560
Oklahoma $38,750 $31,880 $47,640
Oregon $50,410 $43,760 $62,160
Pennsylvania $43,920 $36,810 $48,500
Rhode Island $47,190 $39,280 $56,840
South Carolina $41,160 $34,730 $49,110
South Dakota $41,870 $35,980 $48,960
Tennessee $39,570 $34,840 $48,540
Texas $39,520 $31,200 $49,260
Utah $45,360 $35,890 $56,260
Vermont $47,250 $40,570 $58,420
Virginia $44,740 $37,090 $52,000
Washington $59,290 $46,540 $74,200
West Virginia $37,180 $30,890 $45,350
Wisconsin $48,680 $39,480 $57,990
Wyoming $40,920 $31,200 $51,840

Source: U.S. Bureau of Labor Statistics (BLS) 2024 median salary; projected job growth through 2034. Actual salaries may vary depending on location, level of education, years of experience, work environment, and other factors. Salaries may differ even more for those who are self-employed or work part time.

Physician Assistants

National data

Median Salary: $135,880

Projected job growth: 21.1%

10th Percentile: $99,380

25th Percentile: $120,670

75th Percentile: $163,980

90th Percentile: $190,280

Projected job growth: 21.1%

State data

State Median Salary Bottom 10% Top 10%
Alabama $104,960 $83,020 $145,100
Alaska $150,700 $106,060 $201,270
Arizona $134,650 $106,030 $174,420
Arkansas $118,430 $88,160 $159,080
California $165,650 $99,380 $225,190
Colorado $134,540 $104,590 $174,090
Connecticut $139,860 $106,380 $180,900
Delaware $139,350 $108,560 $175,970
District of Columbia $135,140 $84,520 $213,560
Florida $129,620 $98,530 $181,610
Georgia $115,390 $62,230 $172,050
Hawaii $164,050 $79,280 $178,110
Idaho $133,790 $100,590 $160,120
Illinois $131,950 $105,160 $162,330
Indiana $132,050 $105,810 $196,280
Iowa $134,770 $102,330 $182,940
Kansas $125,640 $98,280 $168,480
Kentucky $120,760 $79,550 $161,820
Louisiana $128,870 $100,920 $162,200
Maine $131,170 $107,630 $169,250
Maryland $137,560 $110,190 $174,280
Massachusetts $142,410 $65,220 $204,140
Michigan $131,510 $104,000 $162,570
Minnesota $141,190 $112,390 $183,320
Mississippi $105,920 $44,030 $165,630
Missouri $135,130 $82,690 $169,650
Montana $141,470 $112,200 $165,560
Nebraska $133,040 $103,720 $165,540
Nevada $134,660 $60,040 $175,300
New Hampshire $150,960 $119,540 $175,380
New Jersey $165,690 $117,860 $207,000
New Mexico $139,920 $70,010 $172,900
New York $160,880 $106,440 $201,410
North Carolina $129,360 $101,100 $164,770
North Dakota $133,450 $77,300 $173,860
Ohio $132,090 $96,460 $210,350
Oklahoma $136,550 $102,890 $173,010
Oregon $155,780 $123,100 $198,490
Pennsylvania $127,070 $99,050 $158,690
Rhode Island $139,930 $98,760 $200,030
South Carolina $122,490 $77,620 $158,860
South Dakota $133,200 $104,660 $158,020
Tennessee $118,240 $93,380 $141,670
Texas $134,550 $102,650 $169,000
Utah $134,740 $82,910 $171,430
Vermont $150,490 $112,460 $186,960
Virginia $135,940 $98,330 $213,010
Washington $164,360 $125,580 $218,150
West Virginia $128,610 $98,200 $160,890
Wisconsin $133,950 $102,420 $169,150
Wyoming $136,080 $102,320 $177,900

Source: U.S. Bureau of Labor Statistics (BLS) 2024 median salary; projected job growth through 2034. Actual salaries may vary depending on location, level of education, years of experience, work environment, and other factors. Salaries may differ even more for those who are self-employed or work part time.

Job Growth

Job growth national average for all careers through 2034 is 3% says the U.S. Bureau of Labor Statistics. Here’s how medical assistants and PAs compare:

Medical Assistant projected job growth through 2034: 12.9%

Physician Assistant projected job growth through 2034: 21.1%

What’s Next?


  • Medical assistant: Many medical assistants move on to positions with more specialized responsibilities such as office managers or nurses.
  • Physician assistant: With some additional education and on-the-job training, PAs can specialize in areas such as internal medicine, oncology, emergency medicine, pediatrics and neonatology.