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Medical Assistant vs. Physician Assistant: What’s the Difference?

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By: All Allied Health Staff

Updated: December 10, 2025

Home » Blog » Medical Assistant vs. Physician Assistant

Just because a health care career has the word “assistant” in its job title, it doesn’t necessarily mean your education will be less strenuous or a less of a commitment to time and effort than other roles—or that your duties will be confined to that of an aide and helper. A good example of two health care careers that could not be more different—but might be confusing due to assistant being in the title—are Medical Assistant and Physician Assistant.

Short and sweet, a medical assistant is more of an entry- to-mid level career while as a physician assistant you will assist and perform advanced duties with a practicing physician.

So, while these two in-demand health care professions sound an awful lot alike, they actually share very little in common when it comes to day-to-day tasks, education requirements, and salary. There are vastly different time and commitment levels needed for you to earn your degree, and the job duties and expertise required are also at opposite ends of the spectrum.

Medical assistants handle a wide variety of entry-level administrative and clinical tasks, whereas physician assistants are licensed health care providers who diagnose and treat patients under the supervision of a physician.

If you’re just entering the health care field, you’ll want to consider a medical assistant career. If you’ve been in the field, have your bachelor’s degree, and are looking to move up the ladder, earning your master’s degree and pursuing your national certification from an accredited PA training program may be the course for you.

Main Differences Between Medical and Physician Assistants

Here are all of the key differences for both careers side-by-side:

Job Duties


Medical Assistant

Physician Assistant

  • Perform administrative tasks, such as updating medical records and arranging for lab services, and clinical duties, such as taking medical histories and recording vital signs.
  • Practice medicine under a physician’s supervision, often serving as the principal health care provider in rural or inner-city clinics.

Education


Medical Assistant

Physician Assistant

Licensing and Certification


Medical Assistant

Physician Assistant

  • To become a certified medical assistant, you must graduate from an accredited medical assistant training program and pass a certifying exam. You can work as an MA without being certified, but most employers and some states require certification for MAs to do things like draw blood.
  • You must be licensed by a state board to practice as a physician assistant. To be eligible for a PA license, you have to pass a national certifying exam, which requires that you graduate from an accredited physician assistant training program.

Median Annual Salaries

The difference in salary between medical assistants and physician assistant roles is notable. Take a look at median annual salaries, as reported by the U.S. Bureau of Labor Statistics.

Medical Assistants

National data

Median Salary: $44,200

Projected job growth: 12.5%

10th Percentile: $35,020

25th Percentile: $37,610

75th Percentile: $48,160

90th Percentile: $57,830

Projected job growth: 12.5%

State data

State Median Salary Bottom 10% Top 10%
Alabama $34,980 $28,280 $43,530
Alaska $51,860 $43,680 $66,820
Arizona $45,440 $37,840 $50,580
Arkansas $37,150 $30,620 $45,750
California $48,050 $37,610 $75,180
Colorado $47,270 $38,010 $57,990
Connecticut $46,500 $37,710 $58,880
Delaware $41,830 $34,270 $51,170
District of Columbia $49,740 $39,000 $62,630
Florida $41,380 $35,320 $48,520
Georgia $39,000 $31,130 $48,950
Hawaii $48,820 $39,090 $58,690
Idaho $43,400 $35,340 $55,700
Illinois $45,490 $35,560 $54,960
Indiana $42,390 $35,930 $48,550
Iowa $43,670 $36,190 $50,950
Kansas $39,090 $33,030 $47,920
Kentucky $38,750 $30,220 $47,100
Louisiana $35,870 $26,580 $42,450
Maine $46,540 $38,480 $57,060
Maryland $45,060 $37,040 $55,500
Massachusetts $48,540 $40,190 $60,850
Michigan $38,840 $35,090 $47,280
Minnesota $49,380 $39,560 $58,910
Mississippi $34,800 $28,080 $44,600
Missouri $39,310 $33,370 $46,940
Montana $45,440 $37,750 $53,010
Nebraska $46,080 $35,620 $56,990
Nevada $43,450 $35,280 $49,260
New Hampshire $48,040 $38,300 $57,580
New Jersey $46,280 $35,150 $57,470
New Mexico $39,000 $33,140 $50,220
New York $46,040 $36,980 $58,250
North Carolina $42,600 $34,920 $51,720
North Dakota $41,040 $35,430 $56,620
Ohio $40,430 $35,270 $48,300
Oklahoma $37,580 $31,200 $46,310
Oregon $49,900 $40,830 $61,100
Pennsylvania $42,810 $35,720 $49,890
Rhode Island $45,820 $38,390 $51,430
South Carolina $38,820 $31,240 $47,120
South Dakota $39,350 $31,450 $47,840
Tennessee $38,150 $32,180 $48,080
Texas $38,930 $30,160 $48,350
Utah $43,040 $34,990 $50,930
Vermont $45,330 $39,310 $52,720
Virginia $42,310 $35,040 $48,510
Washington $55,120 $43,810 $69,320
West Virginia $35,860 $28,620 $43,190
Wisconsin $47,610 $38,440 $55,880
Wyoming $39,240 $31,340 $49,180

Source: U.S. Bureau of Labor Statistics (BLS) 2024 median salary; projected job growth through 2034. Actual salaries may vary depending on location, level of education, years of experience, work environment, and other factors. Salaries may differ even more for those who are self-employed or work part time.

Physician Assistants

National data

Median Salary: $133,260

Projected job growth: 20.4%

10th Percentile: $95,240

25th Percentile: $113,770

75th Percentile: $160,160

90th Percentile: $182,200

Projected job growth: 20.4%

State data

State Median Salary Bottom 10% Top 10%
Alabama $101,620 $57,470 $152,510
Alaska $136,350 $69,970 $185,300
Arizona $135,240 $108,750 $183,470
Arkansas $103,550 $32,970 $153,410
California $161,080 $94,870 $219,300
Colorado $131,910 $99,960 $178,060
Connecticut $138,440 $100,000 $177,780
Delaware $138,720 $103,530 $175,560
District of Columbia $131,070 $81,860 $206,270
Florida $127,200 $83,990 $175,080
Georgia $109,990 $59,990 $157,130
Hawaii $163,020 $67,030 $172,020
Idaho $129,000 $100,120 $154,050
Illinois $122,990 $102,420 $156,340
Indiana $132,200 $104,990 $202,790
Iowa $133,400 $108,400 $172,510
Kansas $124,440 $98,800 $166,400
Kentucky $110,300 $53,040 $148,030
Louisiana $129,610 $65,000 $162,650
Maine $131,250 $105,250 $169,080
Maryland $134,100 $105,870 $170,560
Massachusetts $138,090 $63,860 $192,200
Michigan $131,980 $104,540 $158,620
Minnesota $139,300 $116,450 $169,690
Mississippi $104,570 $39,250 $160,950
Missouri $139,200 $98,440 $168,000
Montana $132,980 $102,130 $159,660
Nebraska $128,240 $101,870 $163,410
Nevada $133,450 $50,450 $196,480
New Hampshire $137,330 $110,690 $174,920
New Jersey $140,490 $107,070 $198,730
New Mexico $139,990 $95,640 $223,250
New York $152,650 $103,210 $204,870
North Carolina $128,540 $99,460 $161,480
North Dakota $126,180 $74,300 $149,970
Ohio $126,760 $98,280 $168,600
Oklahoma $130,750 $51,990 $167,510
Oregon $149,130 $101,920 $206,480
Pennsylvania $124,880 $97,350 $154,640
Rhode Island $141,600 $110,240 $187,830
South Carolina $119,190 $67,750 $149,510
South Dakota $128,130 $102,720 $154,050
Tennessee $113,990 $91,830 $136,970
Texas $132,810 $102,490 $172,790
Utah $134,390 $95,290 $164,900
Vermont $138,610 $106,500 $172,390
Virginia $135,490 $95,250 $186,600
Washington $156,990 $121,740 $201,950
West Virginia $122,970 $65,380 $158,200
Wisconsin $132,820 $107,170 $163,370
Wyoming $133,330 $101,140 $171,130

Source: U.S. Bureau of Labor Statistics (BLS) 2024 median salary; projected job growth through 2034. Actual salaries may vary depending on location, level of education, years of experience, work environment, and other factors. Salaries may differ even more for those who are self-employed or work part time.

Job Growth

Job growth national average for all careers through 2034 is 3% says the U.S. Bureau of Labor Statistics. Here’s how medical assistants and PAs compare:

Medical Assistant projected job growth through 2034: 12.5%

Physician Assistant projected job growth through 2034: 20.4%

What’s Next?


  • Medical assistant: Many medical assistants move on to positions with more specialized responsibilities such as office managers or nurses.
  • Physician assistant: With some additional education and on-the-job training, PAs can specialize in areas such as internal medicine, oncology, emergency medicine, pediatrics and neonatology.